Wait…Echinacea for Anxiety? Isn’t it an Immune Herb?

ARTICLE BY | Dan Stearns

If you feel a little confused by the idea of echinacea to relieve occasional anxiety, it’s understandable. But the fact is, while echinacea is well known for bolstering the immune system, a specialized extract can calm the nerves.*

The clinicallystudied echinacea for anxiety relief (EP107™) is a specific extract of Echinacea angustifolia. The echinacea most associated with relieving cold and flu symptoms is Echinacea purpurea.

It all started as a unique discovery that came about at the Hungarian Academy of Sciences. While analyzing different species of the botanical, they found that some of the plants contained unique compounds, called alkamides, which support healthy brain and stress responses, and cannabinoid receptor activity.

You’ve probably heard a lot about endocannabinoids and cannabinoid receptors, especially with the popularity of hemp oil.

Endocannabinoids are naturally-occurring compounds in the mind and body that have astonishing health-supporting abilities. Two of the most documented of them are anandamide (AEA) and 2-arachidonylglycerol (2-AG). Since anandamide incorporates the Sanskrit word “Ananda” or “bliss” into its name, you can see how maintaining healthy levels of the compound could support a person’s positive mindset as well. Two of the cannabinoid receptors are frequently abbreviated as CB1 and CB2, and roughly divided into support for the mind and body respectively.

Learn more about AnxioCalm®The researchers in Hungary discovered that the levels of alkamides from Echinacea angustifolia were the only ones out of all species tested that best interacted with CB1 and CB2 receptors, virtually mimicking the actions of anandamide. These alkamides also support healthy levels of anandamide by balancing the activity of an enzyme called fatty acid amid hydrolase (FAAH).

Putting these findings to the test, researchers found that the specialized extract in AnxioCalm® has shown impressive results for individuals dealing with occasional anxiety, nervousness, and restless sleep.*

Clinical research published in the journal Phytotherapy Research, shows fast-acting results. Participants were scheduled to use this specialized Echinacea angustifolia extract (EP107) for one week and evaluate their anxiety before, during, and after using the product. But in just three days anxiety levels were significantly lower. Plus, the effects remained stable for the duration of the clinical trial and even for two weeks following treatment—all without drowsiness or other unwanted effects.*

And many people who take AnxioCalm notice a difference on the very first day of use. This makes it an excellent choice before dealing with any number of stressful events you might encounter regularly like air travel, presentations at work, or a busy commute.

So yes, the right extract of the right echinacea really can make a difference for anxiety.* You just have to choose wisely.


Dan is a health and medical writer who primarily focuses on botanical ingredients, whole foods, and natural medicine. He is fascinated with traditional medicine practices and has a diverse background in reporting, editing, publishing, and marketing.

†Relieves occasional anxiety and stress.